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主要文件

810194P

Avanti

18:1-06:0 NBD PS

Avanti Research - A Croda Brand

别名:

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt)

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About This Item

经验公式(希尔记法):
C36H61N6O13P
分子量:
816.88
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 1 mg (810194P-1mg)

制造商/商品名称

Avanti Research - A Croda Brand

运输

dry ice

储存温度

−20°C

一般描述

Phosphatidylserine (PS) is an acidic phospholipid enriched in human cerebral cortex. It is abundant in the inner leaflet of the plasma membrane in neural tissues. NBD PS is a fluorescently labeled phospholipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.

应用

18:1-06:0 NBD PS or 1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) may be used as a marker to determine the aminophospholipid transferase activity and in large unilammelar vesicles (LUVs) to investigate the role of phosphatidylinositol 4,5-bisphosphate (PIP2).

生化/生理作用

Phosphatidylserine (PS) is involved in the regulation of many enzymes and structural components. It supports neuronal survival, neurite growth and synaptogenesis. It is associated with cognitive disability in Alzheimer′s disease.

包装

5 mL Amber Glass Screw Cap Vial (810194P-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


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Phosphatidylserine and the human brain
Glade MJ and Smith K
Nutrition null
Organization and dynamics of N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-labeled lipids: a fluorescence approach
Mukherjee S, et al.
Chemistry and Physics of Lipids null
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research null
R A Zager et al.
Kidney international, 55(1), 148-159 (1999-01-20)
Fluorinated anesthetics can profoundly alter plasma membrane structure and function, potentially impacting cell injury responses. Because major surgery often precipitates acute renal failure, this study assessed whether the most commonly used fluorinated anesthetic, isoflurane, alters tubular cell responses to toxic
Metabolism and functions of phosphatidylserine
Vance JE and Steenbergen R
Progress in Lipid Research null

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