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文件

810188P

Avanti

TopFluor™ TMR PI

Avanti Research™ - A Croda Brand 810188P, powder

别名:

TopFluor™ TMR PI, 1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3a,4a-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3-phosphoinositol (Ammonium salt)

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About This Item

CAS号:
2260795-35-3
UNSPSC代码:
12352211
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 50 μg (with stopper and crimp cap (810188P-50ug))

制造商/商品名称

Avanti Research™ - A Croda Brand 810188P

运输

dry ice

储存温度

−20°C

相关类别

一般描述

Phosphatidylinositol (PI) is commonly found in animal tissues and bacteria. PI is soluble in water and chloroform/methanol. TopFluor™ TMR PI is a tetramethylrhodamine (TMR)-labeled fluorescent phospholipid.

应用

TopFluor™ TMR PI has been used in fluorescence quenching of 1-palmitoyl-2-{12-[(7-nitro-2−1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphatidylcholine (NBD PC) in ternary mixtures of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine (POPC)/ 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylethanolamine(POPE)/ soy l-α-phosphatidylinositol (PI) vesicles.

生化/生理作用

TopFluor™-labeled lipids have spectral properties similar to tetramethylrhodamine (TMR).

包装

2 mL Amber Serum Vial with Stopper and Crimp Cap (810188P-50ug)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available

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Lipids of membranes: Chemistry, biological role and applications as drug carriers
Hatziantonioy S and Demetzos C
Studies in Natural Products Chemistry, 34, 173-202 (2008)
Yi Wen et al.
Biophysical journal, 114(11), 2630-2639 (2018-06-07)
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2 or PIP2), is a key component of the inner leaflet of the plasma membrane in eukaryotic cells. In model membranes, PIP2 has been reported to form clusters, but whether these locally different conditions could give rise to
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
Ann C Kimble-Hill et al.
The journal of physical chemistry. B, 122(35), 8404-8415 (2018-06-08)
Phosphatidylinositol (PI) lipids are necessary for many cellular signaling pathways of membrane associated proteins, such as angiomotin (Amot). The Amot family regulates cellular polarity, growth, and migration. Given the low concentration of PI lipids in these membranes, it is likely

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