810185P
Avanti
TopFluor™ PI(4)P
Avanti Research™ - A Croda Brand 810185P, powder
别名:
1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-4-phosphate (ammonium salt)
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所有图片(1)
About This Item
经验公式（希尔记法）:
C50H88BF2N5O17P2
CAS号:
分子量:
1142.01
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
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方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 50 μg (with stopper and crimp cap (810185P-50ug))
制造商/商品名称
Avanti Research™ - A Croda Brand 810185P
运输
dry ice
储存温度
−20°C
一般描述
Phosphatidylinositol 4-phosphate (PI4P) is a precursor of phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P2]. It is present in the membranes of Golgi apparatus.
应用
TopFluor™ PI(4)P has been used as fluorescently labeled phosphoinositide to examine phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) interaction with anionic lipids.
包装
2 mL Amber Serum Vial with Stopper and Crimp Cap (810185P-50ug)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
Biophysical methods for the characterization of PTEN/lipid bilayer interactions
Harishchandra RK, et al.
Methods, 77, 125-135 (2015)
Xiaojun Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 32(7), 1732-1741 (2016-02-02)
Phosphatidylinositol phosphate (PIP) lipids are critical to many cell signaling pathways, in part by acting as molecular beacons that recruit peripheral membrane proteins to specific locations within the plasma membrane. Understanding the biophysics of PIP-protein interactions is critical to developing
PI4P and PI (4, 5) P2 are essential but independent lipid determinants of membrane identity
Hammond GRV, et al.
Science, 337(6095), 727-730 (2012)
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