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方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810176P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810176P
运输
dry ice
储存温度
−20°C
一般描述
Phosphatidic acid (PA) is an anionic cellular glycerophospholipid constituting 1-4% of membrane lipids. It possesses a phosphomonoester polar head group and two long hydrophobic acyl chains. NBD PA is a fluorescently labelled lipid with the fluorophore, 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the sn-2 fatty acid of PA.
应用
18:1-12:0 NBD PA or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt) is suitable: for the in vitro enzyme activity assay of galactolipase, for NBD-PA and NBD phosphatidyl choline uptake assays, to measure lipid transfer specificity of Ups1 mutants
生化/生理作用
Phosphatidic acid (PA) is implicated in many membrane fusion and membrane fission events, such as fission of Golgi membranes. It is a bioactive lipid and a secondary messenger.
包装
5 mL Amber Glass Screw Cap Vial (810176P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
Lipid second messengers and Receptors
Encyclopedia of Endocrine Diseases, 77(3), 329-334 (2004)
Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins
Miliara X, et al.
Nature Communications, 10(1), 1130-1130 (2019)
Anh H Ngo et al.
The New phytologist, 219(1), 163-175 (2018-04-15)
Phospholipases play crucial roles in plant membrane lipid homeostasis. Nonspecific phospholipase C (NPCs) establish a unique class of phospholipases found only in plants and certain bacteria. Here, we show that two previously uncharacterized NPC isoforms, NPC2 and NPC6, are required
Xeni Miliara et al.
Nature communications, 10(1), 1130-1130 (2019-03-10)
Conserved lipid transfer proteins of the Ups/PRELI family regulate lipid accumulation in mitochondria by shuttling phospholipids in a lipid-specific manner across the intermembrane space. Here, we combine structural analysis, unbiased genetic approaches in yeast and molecular dynamics simulations to unravel
John-Paul Andersen et al.
Molecular metabolism, 42, 101055-101055 (2020-08-02)
Cholesterol plays a pivotal role in mitochondrial steroidogenesis, membrane structure, and respiration. Mitochondrial membranes are intrinsically low in cholesterol content and therefore must be replenished with cholesterol from other subcellular membranes. However, the molecular mechanisms underlying mitochondrial cholesterol transport remains
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