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主要文件

810175P

Avanti

18:1-06:0 NBD PA

Avanti Research - A Croda Brand

别名:

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphate (ammonium salt)

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About This Item

经验公式(希尔记法):
C33H56N5O11P
分子量:
729.80
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25

方案

>99% (TLC)

表单

powder

包装

pkg of 5 × 2 mg (810175P-10mg)

制造商/商品名称

Avanti Research - A Croda Brand

运输

dry ice

储存温度

−20°C

一般描述

Phosphatidic acid (PA) is an amphipathic lipid containing a polar head group and two long hydrophobic acyl chains. PA is an anionic and a membrane structural lipid. It acts as a parent compound for more complex membrane phospholipids.

应用

18:1-06:0 NBD PA may be used for study the effects of NBD-PA induced vesiculation on epidermal growth factor receptor (EGFR) endocytosis in mammalian cells and the co-localization of fluorescently-labeled poly(A)-specific ribonuclease (PARN) with the NBD-tagged PA that outlines the close proximity phospholipase D (PLD2) and PARN.

生化/生理作用

Phosphatidic acid (PA) is a bioactive lipid and a secondary messenger. PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers respectively.

包装

5 mL Amber Glass Screw Cap Vial (810175P-10mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Lipid second messengers and Receptors
Encyclopedia of Endocrine Diseases, 77(3), 329-334 (2004)
Bioactive Lipids
An Introduction to Biological Membranes, , number=(, pages=), 453-478 (2016)
Taylor E Miller et al.
Biology open, 6(2), 176-186 (2016-12-25)
The removal of mRNA transcript poly(A) tails by 3'→5' exonucleases is the rate-limiting step in mRNA decay in eukaryotes. Known cellular deadenylases are the CCR4-NOT and PAN complexes, and poly(A)-specific ribonuclease (PARN). The physiological roles and regulation for PARN is
A Chauhan et al.
Neurochemical research, 25(3), 423-429 (2000-04-13)
Fibrillar amyloid beta-protein (Abeta) is the major protein of amyloid plaques in the brains of patients with Alzheimer's disease (AD). The mechanism by which normally produced soluble Abeta gets fibrillized in AD is not clear. We studied the effect of
Interaction of amyloid beta-protein with anionic phospholipids: possible involvement of Lys28 and C-terminus aliphatic amino acids
Chauhan A, et al.
Neurochemical Research, 25(3), 423-429 (2000)

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