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方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 1 mL (810155C-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810155C
浓度
1 mg/mL (810155C-1mg)
运输
dry ice
储存温度
−20°C
一般描述
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe where the fluorescent NBD label is attached to the headgroup of phosphatidylethanolamine. The NBD moiety is known to localize to the membrane interface. Phosphoethanolamine is the second most abundant andmetabolically related aminophospholipid. It is mostly enriched in brain.
应用
18:1-06:0 NBD PE has been used as a liposomal supplement for protein reconstitution into liposomes and scrambling experiments. It may also be used to analyse the temporal fluorescent pattern of Chol-E-NBD.
生化/生理作用
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a vital role as a fluorescent probe in the studies of organization and dynamics of membranes. Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane.
包装
5 mL Amber Glass Screw Cap Vial (810155C-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
法规信息
易制毒化学品（2类）
危险化学品
Synthesis and validation of novel cholesterol-based fluorescent lipids designed to observe the cellular trafficking of cationic liposomes
Kim BK, et al.
Bioorganic & Medicinal Chemistry, 37-50 (2012)
Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F
Alvadia C, et al.
eLife, 37-50 (2012)
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et biophysica acta. General subjects, 37-50 (2012)
Organization and dynamics of N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-labeled lipids: a fluorescence approach
Mukherjee S, et al.
Chemistry and Physics of Lipids, 37-50 (2012)
Bieong-Kil Kim et al.
Bioorganic & medicinal chemistry letters, 25(18), 3893-3896 (2015-08-06)
Cholesterol-based fluorescent lipids with ether linker were synthesized using NBD (Chol-E-NBD) or Rhodamine B (Chol-E-Rh), and the usefulnesses as fluorescent probes for tracing cholesterol-based liposomes were validated. The fluorescent intensities of liposomes containing these modified lipids were measured and observed
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