检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 1 mL (810144C-1mg)
pkg of 5 × 1 mL (810144C-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810144C
浓度
1 mg/mL (810144C-1mg)
1 mg/mL (810144C-5mg)
运输
dry ice
储存温度
−20°C
一般描述
16:0 NBD PE is a headgroup labelled fluorescent phospholipid. Phosphatidylethanolamine (PE) is the most abundant phospholipid in bacteria and the second most abundant in animals, plants and yeast.
应用
16:0 NBD PE is suitable:
- for use in the bilayer, as fluorescent probe, together with encapsulated doxorubicin (DXR) for the preparation of planar-supported lipid bilayers (PSLB) of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)
- used in fluorescence control experiment
- for labelling giant plasma membrane vesicles
生化/生理作用
L-α-Phosphatidylethanolamine maintains membrane integrity.
包装
5 mL Amber Glass Screw Cap Vial (810144C-1mg)
5 mL Amber Glass Screw Cap Vial (810144C-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
危险化学品
易制毒化学品（2类）
Federico Mazur et al.
Langmuir : the ACS journal of surfaces and colloids (2020-02-26)
Synthetic micromotors are evaluated extensively in a range of biomedical, microscale transport, and environmental applications. Fundamental insight into micromotors that exhibit locomotion due to triggered disintegration of their associated liposomes is provided. Directed self-propulsion is observed when the lipid vesicles
1, 2-diacyl-phosphatidylcholine flip-flop measured directly by sum-frequency vibrational spectroscopy
Liu J and Conboy JC
Biophysical Journal, 89(4), 2522-2532 (2005)
Mesha Saeed et al.
International journal of nanomedicine, 14, 2069-2089 (2019-04-17)
Melanoma is the most aggressive form of skin cancer. Chemotherapy at a late stage fails due to low accumulation in tumors, indicating the need for targeted therapy. To increase drug uptake by tumor cells, we have targeted doxorubicin-containing liposomes using
Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles
Sengupta P, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(1), 20-32 (2008)
Liposomes targeted to MHC-restricted antigen improve drug delivery and antimelanoma response
Saeed M, et al.
International journal of nanomedicine, 14, 2069-2069 (2019)
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