所有图片(2)
别名:
1-Oleoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-Glycero-3-Phosphocholine
经验公式（希尔记法）:
C44H76N5O11P
推荐产品
检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 1 mL (810133C-1mg)
pkg of 5 × 1 mL (810133C-5mg)
制造商/商品名称
Avanti Polar Lipids 810133C
浓度
1 mg/mL (810133C-1mg)
1 mg/mL (810133C-5mg)
脂质类型
fluorescent lipids
phospholipids
运输
dry ice
储存温度
−20°C
一般描述
Phosphatidylcholine (PC) is a prime metabolite in eukaryotes glycerolipid metabolism, mainly synthesized in liver. It is a major element of lipoproteins, bile and lung surfactant. NBD PC contains 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) covalently attached to phosphatidylcholine.
应用
18:1-06:0 NBD PC is suitable for:
- the generation giant unilamellar vesicles (GUVs) subjected to fluorescence microscopy
- labelling lipid bilayers formed by vesicle fusion in order to study the lipid distribution by fluorescence microscopy
- the preparation of phospholipid-coated beads
生化/生理作用
7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) functions as a fluorescent analog in biological membranes in order to study the cellular processes.
包装
5 mL Amber Glass Screw Cap Vial (810133C-1mg)
5 mL Amber Glass Screw Cap Vial (810133C-5mg)
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
法规信息
危险化学品
易制毒化学品（2类）
Laura K Cole et al.
Biochimica et biophysica acta, 1821(5), 754-761 (2011-10-08)
Phosphatidylcholine (PC) is the major phospholipid component of all plasma lipoprotein classes. PC is the only phospholipid which is currently known to be required for lipoprotein assembly and secretion. Impaired hepatic PC biosynthesis significantly reduces the levels of circulating very
Haijia Yu et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(16), 4362-4367 (2016-04-05)
Organelles are in constant communication with each other through exchange of proteins (mediated by trafficking vesicles) and lipids [mediated by both trafficking vesicles and lipid transfer proteins (LTPs)]. It has long been known that vesicle trafficking can be tightly regulated
Henry A Boumann et al.
Biochimica et biophysica acta, 1788(7), 1444-1451 (2009-04-21)
Anammox bacteria that are capable of anaerobically oxidizing ammonium (anammox) with nitrite to nitrogen gas produce unique membrane phospholipids that comprise hydrocarbon chains with three or five linearly condensed cyclobutane rings. To gain insight into the biophysical properties of these
Sang-Yeob Kim et al.
PloS one, 12(4), e0174603-e0174603 (2017-04-05)
The removal of unwanted or damaged cells by phagocytes is achieved via a finely regulated cleaning process called efferocytosis. To characterize the mechanisms through which phagocytes control the intake of apoptotic cells, we investigated how the phagocyte's appetite for engulfed
Wan-Chen Lin et al.
Biophysical journal, 90(1), 228-237 (2005-10-11)
A fundamental attribute of cell membranes is transmembrane asymmetry, specifically the formation of ordered phase domains in one leaflet that are compositionally different from the opposing leaflet of the bilayer. Using model membrane systems, many previous studies have demonstrated the
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