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关于此项目
经验公式（希尔记法）:
C38H64N5O11P
化学文摘社编号:
分子量:
797.92
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
18:1-06:0 NBD PC, Avanti Research™ - A Croda Brand 810132C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810132C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810132C
concentration
1 mg/mL (810132C-1mg)
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine (PC) metabolism. 18:1-06:0 NBD PC is a fluorescent lipid analog/probe.
Application
18:1-06:0 NBD PC is suitable for use:
- as a component in preparing lipid solution for bilayer formation
- to use as a single donor in fluorescence resonance energy transfer (FRET) based assay
- to prepare phospholipid-coated beads
Biochem/physiol Actions
NBD‐PC can be used to probe the existence of (Rho‐labeled) protease‐activated receptor (PAR) pepducins in the outer and inner leaflets.
Packaging
5 mL Amber Glass Screw Cap Vial (810132C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Anticoagulant and antithrombotic properties of intracellular protease-activated receptor antagonists
Wielders SJH, et al.
Journal of Thrombosis and Haemostasis, 5(3), 571-576 (2007)
Coordinated balance of Rac1 and RhoA plays key roles in determining phagocytic appetite
Kim SY, et al.
PLoS ONE, 12(4), e0174603-e0174603 (2017)
Large scale biomimetic membrane arrays
Hansen JS, et al.
Analytical and Bioanalytical Chemistry, 395(3), 719-727 (2009)
Yuta Ryoden et al.
Journal of immunology (Baltimore, Md. : 1950), 204(3), 559-568 (2019-12-22)
In response to extracellular ATP, the purinergic receptor P2X7 mediates various biological processes, including phosphatidylserine (PtdSer) exposure, phospholipid scrambling, dye uptake, ion transport, and IL-1β production. A genome-wide CRISPR screen for molecules responsible for ATP-induced PtdSer exposure identified a transmembrane
Johan Tornmalm et al.
Scientific reports, 9(1), 18133-18133 (2019-12-04)
Protein-lipid interactions in cellular membranes modulate central cellular functions, are often transient in character, but occur too intermittently to be readily observable. We introduce transient state imaging (TRAST), combining sensitive fluorescence detection of fluorophore markers with monitoring of their dark
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