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方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 5 mg (800730P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 800730P
脂质类型
phosphoglycerides
bioactive lipids
运输
dry ice
储存温度
−20°C
一般描述
N-palmitoyl-L-serine methyl ester is an amino acid amphiphile. It is synthesized synthetically from N-succinimidyl palmitate, L-serine methyl ester hydrochloride and triethyl amine.
生化/生理作用
N-palmitoyl-L-serine methyl ester hydrochloride is used for the synthesis of N-palmitoyl-O-phosphocholine serine (PPCS), which is a prime lipid biomarker in Niemann-Pick disease type C1. It is also used for preparation of amino acid based gelators for drug delivery studies.
包装
5 mL Amber Glass Screw Cap Vial (800730P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Systematic modifications of amino acid-based organogelators for the investigation of structure-property correlations in drug delivery system
International Journal of Pharmaceutics, 547(1-2), 637-647 (2018)
N-acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease
Journal of Lipid Research, 60(8), 1410-1424 (2019)
Physical chemistry chemical physics : PCCP, 21(1), 96-103 (2018-12-07)
The monolayers of N-alkanoyl substituted threonine amphiphiles, similar to those of other N-alkanoyl-substituted amino acid amphiphiles, point to substantial differences in the main characteristics compared to usual amphiphilic monolayers. π-A measurements of the enantiomeric and racemic forms of N-alkanoyl-substituted threonine
Journal of lipid research, 60(8), 1410-1424 (2019-06-16)
Niemann-Pick disease type C1 (NPC1) is a fatal, neurodegenerative, cholesterol storage disorder. With new therapeutics in clinical trials, there is an urgency to improve diagnostics and monitor therapeutic efficacy with biomarkers. In this study, we sought to define the structure
Special features of monolayer characteristics of N-alkanoyl substituted threonine amphiphiles
Physical Chemistry Chemical Physics, 21(1), 96-103 (2019)
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