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检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 5 mg (791661P-5mg)
制造商/商品名称
Avanti Polar Lipids 791661P
运输
dry ice
储存温度
−20°C
一般描述
N-palmitoyl(d9) dihydrosphingosine is a deuterated form of N-palmitoyl dihydrosphingosine (N16DS18). N16DS18 is a N-acyl dihydrosphingosine (NDS) present in human hair. NDS acyl chains comprise 2-24 carbons.
应用
N-palmitoyl(d9) dihydrosphingosine CER10(d9) has been used as a deuterium-labeled ceramide internal standard in lipid extraction from human and mouse stratum corneum (SC) samples for liquid chromatography tandem-mass spectrometry (LC–MS/MS) analysis.
生化/生理作用
Dihydrosphingosine provides protection to the skin by acting as a lipid barrier.
包装
5 mL Amber Glass Screw Cap Vial (791661P-5mg)
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
法规信息
美国出口管控1C298产品
Yoshinori Masukawa et al.
Journal of chromatography. A, 1127(1-2), 52-59 (2006-06-20)
An analytical method for highly sensitive determination of four N-acyl dihydrosphingosines (NDSs) of all ceramides (CERs) in human hair, such as N-palmitoyl dihydrosphingosine (N16DS18), N-stearoyl dihydrosphingosine (N18DS18), N-lignocerol dihydrosphingosine (N24DS18) and N-nervonoyl dihydrosphingosine (N24:1DS18), has been developed using electrospray ionization
Barbora Školová et al.
Biochimica et biophysica acta. Biomembranes, 1859(5), 824-834 (2017-01-23)
Ceramides based on phytosphingosine, sphingosine and dihydrosphingosine are essential constituents of the skin lipid barrier that protects the body from excessive water loss. The roles of the individual ceramide subclasses in regulating skin permeability and the reasons for C4-hydroxylation of
Momoko Kawana et al.
Journal of lipid research, 61(6), 884-895 (2020-04-09)
Ceramides are the predominant lipids in the stratum corneum (SC) and are crucial components for normal skin barrier function. Although the composition of various ceramide classes in the human SC has been reported, that in mice is still unknown, despite
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