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检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 1 mL (791645C-1mg)
制造商/商品名称
Avanti Polar Lipids 791645C
浓度
1 mg/mL (791645C-1mg)
运输
dry ice
储存温度
−20°C
一般描述
Cholesteryl oleate is a cholesteryl ester. 18:1-d7-cholesterol is a deuterated oleic acid cholesteryl ester.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH® LIPIDOMIX® Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
应用
18:1-d7-cholesterol may be used in the reconstitution of acetylated low-density lipoprotein (acLDL) liposome for trafficking studies in U2OS-SRA cells.
生化/生理作用
Elevation in cholesterol ester levels and its accumulation is implicated in prostate cancer (PCa). Cholesteryl oleate, may serve as a potential biomarker for diagnosis of PCa.
包装
5 mL Clear Glass Sealed Ampule (791645C-1mg)
法律信息
LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.
SPLASH is a registered trademark of Avanti Polar Lipids, Inc.
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
法规信息
易制毒化学品（2类）
危险化学品
Heart Proteomics, 967-1009 (2001)
Jia Li et al.
Scientific reports, 6, 20984-20984 (2016-02-13)
In-depth delineation of lipid metabolism in prostate cancer (PCa) is significant to open new insights into prostate tumorigenesis and progression, and provide potential biomarkers with greater accuracy for improved diagnosis. Here, we performed lipidomics and transcriptomics in paired prostate cancer
McKenna Feltes et al.
Journal of lipid research, 60(3), 707-716 (2019-01-09)
Cholesterol is an essential structural component of cellular membranes and precursor molecule for oxysterol, bile acid, and hormone synthesis. The study of intracellular cholesterol trafficking pathways has been limited in part due to a lack of suitable cholesterol analogues. Herein
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