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安全信息

791640C

Avanti

15:0-18:1-d7-PG

Avanti Research - A Croda Brand 791640C

别名:

1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] (sodium salt)

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About This Item

经验公式(希尔记法):
C39H67D7NaO10 P
分子量:
764.01
UNSPSC代码:
41141825
NACRES:
NA.25

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 1 mL (791640C-1mg)

制造商/商品名称

Avanti Research - A Croda Brand 791640C

浓度

1 mg/mL (791640C-1mg)

运输

dry ice

储存温度

−20°C

一般描述

15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] is a deuterated phospholipid. The lipid comprises phosphatidylglycerol attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylglycerol is anionic phospholipid and is associated with thylakoids, microsomal and mitochondrial membrane.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH LIPIDOMIX Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

应用

15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] (sodium salt),) has been used:
  • as a component of extraction solvent for lipid isolation from biological samples
  • as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis
  • as an isotopically labeled lipid internal standard for correction of lipids detected in lipid droplets using shotgun mass spectrometry analysis

生化/生理作用

Phosphatidylglycerol (PG) plays a key role in photosynthesis. Cardiolipin is synthesized from PG. PG mediates many mitochondrial functions.

包装

2 mL Amber Glass Sealed Ampule (791640C-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品(2类)
危险化学品

分析证书(COA)

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Shin-Ya Morita et al.
Scientific reports, 5, 11737-11737 (2015-07-01)
Phosphatidylglycerol (PG) and cardiolipin (CL) are synthesized in mitochondria and regulate numerous biological functions. In this study, a novel fluorometric method was developed for measuring PG and CL using combinations of specific enzymes and Amplex Red. This assay quantified the
Ya Xie et al.
Food chemistry, 319, 126547-126547 (2020-03-18)
In this research, a novel ultrasound-assisted extraction (USAE) method using a one-phase solvent (isopropanol, IPA) combined with liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QToF-MS) was developed for exhaustive profiling of egg yolk lipids, which are considered to be essential
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
Florian Geltinger et al.
GeroScience, 42(1), 19-38 (2019-11-05)
Originally Lipid droplets (LDs) were considered as being droplets for lipid storage only. Increasing evidence, however, demonstrates that LDs fulfill a pleiotropy of additional functions. Among them is the modulation of protein as well as lipid homeostasis. Under unfavorable pro-oxidative

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