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检测方案
>99% (TLC)
形式
liquid
包装
pkg of 1 × 1 mL (791638C-1mg)
制造商/商品名称
Avanti Polar Lipids
浓度
1 mg/mL (791638C-1mg)
运输
dry ice
储存温度
−20°C
一般描述
15:0-18:1-d7-PE (1-十五酰基-2-油酰基(d7)-sn-丙三基-3-磷酸乙醇胺)是氘代磷脂。该脂质包括与十五烷酸和油酸相连的磷脂酰乙醇胺。油酸为氘离子提供庇护。磷脂酰乙醇胺是一种膜磷脂，在其他甘油磷脂合成中充当中间体。
这种氘标记脂质也可在多种脂质标准的配方中获得。SPLASH® LIPIDOMIX®标准品包括与人血浆的所有主要脂质类别对应的脂质，从而实现一种简单的内标溶液适用每种样品。
应用
15:0-18:1-d7-PE (1-十五酰基-2-油酰基(d7)-sn-丙三基-3-磷酸乙醇胺)已用于：
- 作为生物样品中脂质分离的萃取溶剂组分，
- 作为液相色谱串联质谱法(LC-MS/MS)测定血清样品的内部标准品
- 作为傅立叶变换质谱(FTMS)分析中刺穿血浆样品的内部标准品
生化/生理作用
磷脂酰乙醇胺(PE)调节蛋白质折叠、蛋白质修饰、自噬和细胞分裂。PE作为糖基磷脂酰肌醇锚定蛋白(GPI-AP)合成的底物。低水平的PE可见于帕金森病，也可抑制蛋白质成熟。
包装
2 mL棕色玻璃密封安瓿（791638C-1mg）
法律信息
LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.
SPLASH is a registered trademark of Avanti Polar Lipids, Inc.
通常也和此产品一起购买
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
危险化学品
易制毒化学品（2类）
Total Fatty Acid Analysis of Human Blood Samples in One Minute by High-Resolution Mass Spectrometry.
Sandra F Gallego et al.
Biomolecules, 9(1) (2018-12-29)
Total fatty acid analysis is a routine method in many areas, including lipotyping of individuals in personalized medicine, analysis of foodstuffs, and optimization of oil production in biotechnology. This analysis is commonly done by converting fatty acyl (FA) chains of
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Bjoern Titz et al.
Computational and structural biotechnology journal, 18, 1056-1073 (2020-05-19)
Cigarette smoke (CS) causes adverse health effects and, for smoker who do not quit, modified risk tobacco products (MRTPs) can be an alternative to reduce the risk of developing smoking-related diseases. Standard toxicological endpoints can lack sensitivity, with systems toxicology
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
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