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Merck
CN

791281P

Avanti

α-mycolic acid, methoxy cis

powder

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别名:
Cyclopropaneeicosanoic acid, β-hydroxy-2-[(17S,18S)-17-methoxy-18-methylhexatriacontyl]-α-tetracosyl-, (αR,βR,1R,2S)-
经验公式(希尔记法):
C85H168O4
CAS号:
分子量:
1254.24
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 1 mg (791281P-1mg)

制造商/商品名称

Avanti Polar Lipids 791281P

脂质类型

bacterial lipids

运输

dry ice

储存温度

−20°C

一般描述

α-mycolic acid (MA), methoxy cis comprises 84–88 carbon atoms like the other types keto and hydroxy MA. All the MA types are synthesized from hydroxylated intermediate, with methoxy M generated by the action of enzyme methoxylase.
Mycolic acid is a long Fatty acid found in the cell walls of the mycolata taxon, a group of bacteria that includes Mycobacterium tuberculosis, the causative agent of the disease tuberculosis.

生化/生理作用

Methoxy mycolic acids are antigenic and are specific for pathogenic mycobacterial class. The three types of mycolic acids including the methoxy-MA display variation in their antigenicity with reference to antibody recognition.

包装

5 mL Amber Glass Screw Cap Vial (791281P-1mg)

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Hedia Marrakchi et al.
Chemistry & biology, 21(1), 67-85 (2014-01-01)
Mycolic acids are major and specific lipid components of the mycobacterial cell envelope and are essential for the survival of members of the genus Mycobacterium that contains the causative agents of both tuberculosis and leprosy. In the alarming context of
Nabil Tahiri et al.
Angewandte Chemie (International ed. in English), 59(19), 7555-7560 (2020-02-19)
In Mycobacterium tuberculosis, mycolic acids and their glycerol, glucose, and trehalose esters ("cord factor") form the main part of the mycomembrane. Despite their first isolation almost a century ago, full stereochemical evaluation is lacking, as is a scalable synthesis required
Heena Ranchod et al.
PloS one, 13(8), e0200298-e0200298 (2018-08-10)
Mycolic acids (MA) are major, species-specific lipid components of Mycobacteria and related genera. In Mycobacterium tuberculosis, it is made up of alpha-, methoxy- and keto-MA, each with specific biological functions and conformational characteristics. Antibodies in tuberculosis (TB) patient sera respond

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