790981P
Avanti
14:0 PE-DTPA (Gd)
1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt), powder
别名:
1,2-ditetradecanoyl-sn-glycero-3-phosphoethanolamine- N-diethylenetriaminepentaacetic acid (gadolinium salt); DMPE-DTPA (Gd)
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About This Item
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方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 5 mg (790981P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 790981P
脂质类型
phospholipids
运输
dry ice
储存温度
−20°C
一般描述
14:0 PE-DTPA (Gd) has been used as a paramagnetic lipid to probe the orientation of a membrane protein in respect to the phospholipid bilayer membrane.
Lipid nanoparticles containing DMPE-DTPA(Gd) provide high quality contrast enhanced vascular MRI at 97% reduced dose of Gd and do not rely on renal clearance. Structure as shown by Cormode, D.P. et al.
包装
5 mL Amber Glass Screw Cap Vial (790981P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Alessandra Barazza et al.
Bioconjugate chemistry, 24(6), 1039-1048 (2013-04-27)
We have previously reported enhancing the imaging of atherosclerotic plaques in mice using reconstituted high density lipoproteins (HDL) as nanocarriers for the MRI contrast agent gadolinium (Gd). This study focuses on the underlying mechanisms of Gd delivery to atherosclerotic plaques.
Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR
Hagn F, et al.
Nature Protocols, 13(1), 79-79 (2018)
David P Cormode et al.
Nano letters, 8(11), 3715-3723 (2008-10-23)
High density lipoprotein (HDL) is an important natural nanoparticle that may be modified for biomedical imaging purposes. Here we developed a novel technique to create unique multimodality HDL mimicking nanoparticles by incorporation of gold, iron oxide, or quantum dot nanocrystals
Ivano Bertini et al.
Magnetic resonance in medicine, 52(3), 669-672 (2004-08-31)
In the present research, we investigated the use of paramagnetic liposomes as contrast agents (CAs) for the detection of solid tumors. The liposomes were sterically stabilized by a polyethylene glycol (PEG) coating, and their size was constrained to approximately 100
Nanocrystal core high-density lipoproteins: a multimodality contrast agent platform.
Cormode DP, et al.
Nano Letters, 8, 3715-3723 (2008)
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