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790625C

Avanti

DC-Chol/DOPE混合物

Avanti Polar Lipids 790625C

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别名:
DC-Chol/DOPE Blend, DC-Cholesterol/Dioleoyl Phosphatidylethanolamine (30:70, w/w)
UNSPSC代码:
12352211
NACRES:
NA.25

形式

liquid

包装

pkg of 1 × 2.5 mL (790625C-25mg)

制造商/商品名称

Avanti Polar Lipids 790625C

浓度

10 mg/mL (790625C-25mg)

脂质类型

cationic lipids

运输

dry ice

储存温度

−20°C

一般描述

DC-Chol/DOPE blend is a cationic lipid blend.
DC-Chol/DOPE is a blend of a cationic lipid : 3b-[N-(N′, N′ dimethyl-aminoethane)carbomyl] (DC-Chol ) and a neutral lipid : dioleoyl phosphatidylethanolamine (DOPE).

生化/生理作用

The DC-Chol/DOPE blend is widely useful in liposome preparation as it influences the process of encapsulation. 1:2 or 3:2 is a preferred molar ratio for DC-Chol/DOPE liposomes.

包装

5 mL Clear Glass Sealed Ampule (790625C-25mg)

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

法规信息

易制毒化学品(2类)
危险化学品

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Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease
Leone P, et al.
Annals of Neurology, 48(1), 27-38 (2000)
Shuoye Yang et al.
International journal of pharmaceutics, 434(1-2), 155-160 (2012-05-31)
Three most commonly used preparative methods, dry-film, reverse phase evaporation and ethanol injection were employed to prepare cationic liposomes composed of DC-Chol and DOPE, respectively. The resulting samples were contrasted through morphology observation, particle size and zeta potential analysis. Sephadex

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