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![18:1 DGS-NTA(Co) 1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (Cobalt salt), powder](/deepweb/assets/sigmaaldrich/product/structures/203/482/b877a7a9-e8a9-4cec-99cf-b256a26d690c/640/b877a7a9-e8a9-4cec-99cf-b256a26d690c.png)
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 5 mg (790528P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 790528P
运输
dry ice
储存温度
−20°C
一般描述
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (18:1 DGS-NTA) is amphiphile. DGS-NTA is a nitrilotriacetic acid -functionalized amphiphile devoid of nickel ion.
应用
18:1 DGS-NTA 1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (ammonium salt) has been used:
- for generation of amphiphile monolayer
- in NTA-liposome preparation for procoagulant binding studies and to study its effect on factor FXII autoactivation
- as a liposome component for lipid bilayer preparation for surface plasmon resonance studies
生化/生理作用
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (18:1 DGS-NTA or DOGS-NTA) cannot bind to histidine due to lack of nickel ion. It is capable of self-assembly to form a stable monolayer. DOGS-NTA ammonium salt is useful in bicelle preparation.
包装
5 mL Clear Glass Sealed Ampule (790528P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Louis Gioia et al.
Science immunology, 4(38) (2019-09-01)
The class II region of the major histocompatibility complex (MHC) locus is the main contributor to the genetic susceptibility to type 1 diabetes (T1D). The loss of an aspartic acid at position 57 of diabetogenic HLA-DQβ chains supports this association;
N J Mutch et al.
Journal of thrombosis and haemostasis : JTH, 10(10), 2108-2115 (2012-08-22)
Upon contact with an appropriate surface, factor XII (FXII) undergoes autoactivation or cleavage by kallikrein. Zn(2+) is known to facilitate binding of FXII and the cofactor, high molecular weight kininogen (HK), to anionic surfaces. To investigate whether transition metal ions
Decorating liquid crystal surfaces with proteins for real-time detection of specific protein-protein binding
Hartono D, et al.
Advances in Functional Materials, 19(22), 3574-3579 (2009)
Ronald D Seidel et al.
Journal of the American Chemical Society, 129(15), 4834-4839 (2007-03-28)
The study of bound-state conformations of ligands interacting with proteins is important to the understanding of protein function and the design of drugs that alter function. Traditionally, transferred nuclear Overhauser effects (trNOEs), measured from NMR spectra of ligands in rapid
E Barklis et al.
The EMBO journal, 16(6), 1199-1213 (1997-03-17)
We have developed a system for analysis of histidine-tagged (His-tagged) retrovirus core (Gag) proteins, assembled in vitro on lipid monolayers consisting of egg phosphatidylcholine (PC) plus the novel lipid DHGN. DHGN was shown to chelate nickel by atomic absorption spectrometry
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