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安全信息

790427C

Avanti

06:0 PC-d22

Avanti Research - A Croda Brand 790427C

别名:

1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine

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About This Item

经验公式(希尔记法):
C20H18NO8PD22
分子量:
475.64
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.12

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mL (790427C-10mg)

制造商/商品名称

Avanti Research - A Croda Brand 790427C

浓度

10 mg/mL (790427C-10mg)

运输

dry ice

储存温度

−20°C

一般描述

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Phosphatidylcholine is a zwitterionic glycerophospholipid, containing choline. It consists of a head and two tails. Head group contains choline and phosphate. Head is polar and water soluble. The tail group contains two fatty acyl chains esterified with glycerol. Tail group is non-polar and water-insoluble. Phosphatidylcholine is synthesized in the liver by phosphatidylethanolamine methyltransferase (PEMT) pathway. It is also synthesized by the Kennedy pathway and the Lands cycle.

应用

06:0 PC-d22 (1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine) has been used:
  • as bicelles for lipid in HN-HN nuclear overhauser enhancement (NOE) detection
  • as an internal standard in residual algal suspension for liquid chromatography-mass spectrometry analysis (LC-MS/MS)
  • to produce bicelles to investigate C-peptide and membrane interaction by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY)

生化/生理作用

Phosphatidylcholine (PC) is a major component of the membrane bilayer. It is involved in the synthesis of signaling molecules. PC is the precursor for the synthesis of sphingomyelin and phosphatidylserine.

包装

5 mL Clear Glass Sealed Ampule (790427C-10mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

法规信息

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访问文档库

Metabolic and morphological changes of an oil accumulating trebouxiophycean alga in nitrogen-deficient conditions
Ito T, et al.
Metabolomics, 9(1), 178-187 (2013)
Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage
Moessinger C, et al.
BMC Cell Biology, 15(1), 43-43 (2014)
pH-dependent interaction between C-peptide and phospholipid bicelles
Unnerstaale S and Maler L
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012(1), 43-43 (2012)
Biochemistry of Lipids, Lipoproteins and Membranes (2015)
The unusual transmembrane partition of the hexameric channel of the hepatitis C virus
Chen W, et al.
Structure, 26(4), 627-634 (2018)

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