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检测方案
>99% (TLC)
形式
powder
包装
pkg of 1 × 5 mg (700175P-5MG)
制造商/商品名称
Avanti Polar Lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
CC1(CC[C@H](O)C2)C2=CCC3C1CCC4(C)C3CCC4C(/C=C/[C@H](C)C(C)C)C
InChI
1S/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-9,18-20,22-26,29H,10-17H2,1-6H3/b8-7+/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1
InChI key
OILXMJHPFNGGTO-ZAUYPBDWSA-N
一般描述
Brassicasterol is a plant sterol, sharing similar structure with cholesterol. It is obtained through the dietary sources, including sea food.
应用
- Deciphering the effect of phytosterols on Alzheimer′s disease and Parkinson′s disease: the mediating role of lipid profiles: This research demonstrates the neuroprotective potential of phytosterols, including Brassicasterol, in modulating lipid profiles to mitigate symptoms of neurodegenerative diseases such as Alzheimer′s and Parkinson′s (Guo et al., 2024).
- Liposomal Phytosterols as LDL-Cholesterol-Lowering Agents in Diet-Induced Hyperlipidemia: Discusses the effectiveness of Brassicasterol and other phytosterols encapsulated in liposomes for reducing LDL cholesterol, showcasing a potential therapeutic approach in hyperlipidemia management (Poudel et al., 2023).
- Sterol Regulation of Development and 20-Hydroxyecdysone Biosynthetic and Signaling Genes in Drosophila melanogaster: Highlights the role of Brassicasterol in regulating developmental and hormonal pathways in model organisms, suggesting implications for developmental biology studies (Wen et al., 2023).
生化/生理作用
Brassica sterol in cerebrospinal fluid might serve as an indicator for Alzheimer′s disease. It is found in rapeseed oil. Brassicasterol is thus, useful in identifying brassica oil and contamination of rapeseed and canola oil in others. Plant sterols can penetrate through the blood brain barrier.
包装
5 mL Amber Glass Screw Cap Vial (700175P-5MG)
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
The plant sterol brassicasterol as additional CSF biomarker in Alzheimer?s disease
Vanmierlo T, et al.
Acta Psychiatrica Scandinavica, 124(3), 184-192 (2011)
The search of new biomarkers to identify Alzheimer?s disease: An editorial comment to T. Vanmierlo et al.`The plant sterol brassicasterol and additional CFS biomarker in Alzheimer?s Disease?(1)
Lobo A and Quintanilla MA
Acta Psychiatrica Scandinavica, 124(3), 163-164 (2011)
Rapeseed and Canola Oil: Production, Processing, Properties and Uses, 60-60 (2004)
Analysis of sterol compounds from Sambucus ebulus
Bubulica MV, et al.
Chemistry of Natural Compounds, 1-2 (2012)
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