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安全信息

700149P

Avanti

16:0 cholesteryl-d7 ester

Avanti Research - A Croda Brand 700149P, powder

别名:

cholesteryl-d7 palmitate

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About This Item

经验公式(希尔记法):
C43H69D7O2
分子量:
632.11
MDL编号:
UNSPSC代码:
41141804
NACRES:
NA.25

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 10 mg (700149P-10mg)
pkg of 1 × 25 mg (700149P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand 700149P

运输

dry ice

储存温度

−20°C

一般描述

Cholesteryl palmitate is a cholesteryl ester. 16:0 cholesteryl-d7 ester is the deuterated form of cholesteryl palmitate or 16:0 cholesteryl ester.

应用

16:0 cholesteryl-d7 ester has been used:
  • in plasma sample preparation for tandem mass spectrometry analysis (MS/MS)
  • as an internal standard in mass spectrometry for quantification of nerve lipids from mice
  • as an internal standard in time-of-flight mass spectrometry (TOFMS) for the quantification of serum extracellular vesicles (EVs) lipids
  • as an external calibrator and internal spiking standard in tandem mass spectroscopy measurements
  • in liposome preparation for retinyl ester hydrolase (REH) and cholesteryl esterase activity assay

生化/生理作用

Cholesteryl palmitate is associated with atherosclerotic plaque. Deuterated cholesteryl palmitate in used in reconstituting high-density lipoprotein (HDL). An elevated levels of the ratio of cholesteryl oleate to cholesteryl palmitate is implicated with apoptotic cell death in the atherosclerotic lesions.

包装

5 mL Amber Glass Screw Cap Vial (700149P-10mg)
5 mL Amber Glass Screw Cap Vial (700149P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

通常也和此产品一起购买

产品编号
说明
价格

储存分类代码

11 - Combustible Solids

法规信息

美国出口管控1C298产品

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Suming Chen et al.
Journal of circulating biomarkers, 8, 1849454419879848-1849454419879848 (2019-10-22)
There is a wide variety of extracellular vesicles (EVs) that differ in size and cargo composition. EVs isolated from human plasma or serum carry lipid, protein, and RNA cargo that provides insights to the regulation of normal physiological processes, and
Y I Parmar et al.
The Journal of biological chemistry, 258(3), 2000-2004 (1983-02-10)
Reconstituted high density lipoprotein has been prepared by sonication and preparative ultracentrifugation of mixtures containing the apoprotein of high density lipoprotein, egg phosphatidylcholine, cholesteryl oleate, and acyl chain deuterated cholesteryl palmitate in aqueous buffer. The resulting structures have a size
Michael S Gardner et al.
Journal of the American Society for Mass Spectrometry, 28(11), 2319-2329 (2017-08-13)
We demonstrate the application of in-source nitrogen collision-induced dissociation (CID) that eliminates the need for ester hydrolysis before simultaneous analysis of esterified cholesterol (EC) and triglycerides (TG) along with free cholesterol (FC) from human serum, using normal phase liquid chromatography
Y Zang et al.
Journal of dairy science, 102(2), 1224-1236 (2018-11-26)
Co-supplementation of methyl donors may lower hepatic lipid content in transition cows. To define the ability of methyl donor supplementation (MDS) to reduce hepatic lipid content and modify the plasma lipidome, 30 multiparous Holstein cows (2.04 ± 0.69 lactations; 689
Maidina Tuohetahuntila et al.
The Journal of biological chemistry, 292(30), 12436-12448 (2017-06-16)
Activation of hepatic stellate cells (HSCs) is a critical step in the development of liver fibrosis. During activation, HSCs lose their lipid droplets (LDs) containing triacylglycerols (TAGs), cholesteryl esters, and retinyl esters (REs). We previously provided evidence for the presence

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