方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (700137P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 700137P
运输
dry ice
储存温度
−20°C
一般描述
7β,27-dihydroxycholesterol-d6 is a deuterated derivative of 7β,27-dihydroxycholesterol. 7β,27-dihydroxycholesterol is a substrate for enzyme 11β-hydroxysteroid dehydrogenases (11β-HSDs).
应用
7β,27-dihydroxycholesterol-d6 has been used as an internal standard in ultra-performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS).
生化/生理作用
7β,27-dihydroxycholesterol (7β27OHC) serves as a ligand for retinoid-related orphan receptor γ (RORγ). 7β27OHC is also involved in smoothened (Smo) functionality.
包装
5 mL Amber Glass Screw Cap Vial (700137P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
新产品
Katharina R Beck et al.
Journal of lipid research, 60(9), 1535-1546 (2019-07-06)
Oxysterols previously were considered intermediates of bile acid and steroid hormone biosynthetic pathways. However, recent research has emphasized the roles of oxysterols in essential physiologic processes and in various diseases. Despite these discoveries, the metabolic pathways leading to the different
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