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Merck
CN

640007P

Avanti

Girard Reagent

Avanti Polar Lipids

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别名:
1-(2-hydrazinyl-2-oxoethyl)pyridin-1-ium bromide
经验公式(希尔记法):
C7H10BrN3O
分子量:
232.08
UNSPSC代码:
12352116
NACRES:
NA.28

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 250 mg (640007P-250mg)

制造商/商品名称

Avanti Polar Lipids

运输

dry ice

储存温度

−20°C

一般描述

Girard Reagents are N-substituted glycine hydrazides. They are classified as Girard-T (trimethylacetylhydrazide ammonium chloride), Girard-P (pyridinioacetohydrazide chloride) and Girard-D (N,N-dimethylglycine hydrazide hydrochloride). Girard hydrazones have a quaternary nitrogen moiety.

生化/生理作用

Girard reagents facilitate the isolation of carbonyl compounds from their complex mixtures, by generating water-soluble hydrazones. These reagents are sensitive and selective. Girard P reagent is used for the derivatization of oxosteroids to form the corresponding Girard hydrazones, which can be detected by tandem mass spectroscopy or electrospray (ES) mass spectrometry.

包装

20 mL Clear Glass Screw Cap Vial (640007P-250mg)

分析证书(COA)

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Analysis of oxysterols by electrospray tandem mass spectrometry
Griffiths WJ, et al.
Journal of the American Society For Mass Spectrometry, 17(3), 341-362 (2006)
Transition metal complexes with Girard reagents and their hydrazones
Vojinovic-Jevsic LS, et al.
J. Serb. Chem. Soc., 77(9), 1129-1155 (2012)
Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols
Roberg-Larsen H, et al.
Journal of Lipid Research, 55(7), 1531-1536 (2014)

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