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安全信息

300105S

Avanti

Dox-NP (5mL vial)

Avanti Research - A Croda Brand 300105S

别名:

Dox-NP, Dox-NP (Liposomal Encapsulated Doxorubicin)

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About This Item

UNSPSC代码:
12352202

形式

solution

包装

pkg of 1 × 5 mL (with stopper and crimp cap (300105S-1EA))

制造商/商品名称

Avanti Research - A Croda Brand 300105S

运输

wet ice

储存温度

2-8°C

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一般描述

Concentration: 2 mg/ml doxorubicin HCl at pH 6.5-6.8, in 10 mM histidine buffer, with 10% w/v sucrose.Particle size and shape: Dox-NP mean particle size is 80 to 90 nm, with very small poly-dispersity valuePurity: >=90% of the drug is encapsulated in the long-circulating, pegylated, liposomes.Formulation: The long-circulating, pegylated, liposomal carrier is composed of N-(carbonyl-ethoxypolyethylene glycol 2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine sodium salt (MPEG-DSPE), 3.19 mg/ml; fully hydrogenated soy phosphatidylcholine (HSPC), 9.58 mg/ml; cholesterol, 3.19 mg/ml, ammonium sulfate, approximately 2 mg/ml; histidine as a buffer; hydrochloric acid or sodium hydroxide for pH control; and sucrose to maintain isotonicity. Dox-NP is provided as a sterile, translucent, red liposomal dispersion in single-use, 2 ml or 5 ml vials.Buffer: 10 mM histidine buffer, pH 6.5-6.8, with 10% w/v sucrose.

应用

Intravenous (i.v.) injection in flank or orthotopic animal models of cancer.

包装

10 mL Clear Glass Vial with Stopper and Crimp Cap (300105S-1EA)

储存及稳定性

Store undiluted at 2°-8° C. Do Not Freeze.

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC
Dox-NP is a trademark of Avanti Polar Lipids, LLC

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Carc. 1B - Muta. 1B

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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