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Merck
CN

171204P

Avanti

Heart Extract Polar

Avanti Polar Lipids

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别名:
Heart Polar Lipid Extract (Bovine)
CAS号:
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 100 mg (171204P-100mg)

制造商/商品名称

Avanti Polar Lipids

脂质类型

lipid extracts

运输

dry ice

储存温度

−20°C

一般描述

Heart Extract Polar comprises the neutral lipid as a major component. Other components include phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine and phosphatidylinositol.
Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.

应用

Heart Extract Polar may be used:
  • in the preparation of lipid bilayer membrane for ion channel ICln reconstitution
  • in preparation of model membranes for flow fluorometry studies
  • as a lipid standard in thin-layer chromatography

生化/生理作用

The lipids from the bovine heart mitochondria display a higher phospholipid content compared to liver lipids. Lipid extracts from the mammalian tissues like heart, kidney and liver are used in generating model membranes for mimicking real membranes. These lipid extracts also display nonlamellar phases majorly pertaining to hexagonal, cubic, micellar types at physiological temperatures.

包装

5 mL Clear Glass Sealed Ampule (171204P-100mg)

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ICln channels reconstituted in heart-lipid bilayer are selective to chloride
Garavaglia M, et al.
Pflugers Archiv : European Journal of Physiology, 443(5-6), 748-753 (2002)
Lipid composition of mitochondria from bovine heart, liver, and kidney
Fleischer S, et al.
Journal of Lipid Research, 8(3), 170-180 (1967)
Inorganic mercury and cadmium induce rigidity in eukaryotic lipid extracts while mercury also ruptures red blood cells
Kerek E, et al.
Biochimica et Biophysica Acta - Biomembranes, 1860(3), 710-717 (2018)
Natural lipid extracts and biomembrane-mimicking lipid compositions are disposed to form nonlamellar phases, and they release DNA from lipoplexes most efficiently
Koynova R and MacDonald RC
Biochimica et Biophysica Acta - Biomembranes, 1768(10), 2373-2382 (2007)

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