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描述
L-α-glycerophosphoryl(choline-d9), water:ethanol (9:1)
检测方案
>99% phosphorus (P) basis (qNMR)
形式
solution
包装
pkg of 1 × 1 mL (100403X-100ug)
制造商/商品名称
Avanti Polar Lipids
浓度
0.1 mg/mL (100403X-100ug)
运输
dry ice
储存温度
−20°C
一般描述
GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter.
Glycerophosphocholine (GPC), is a water-soluble deacylated phosphatidylcholine derivative. It is majorly generated from choline based phospholipids associated with membranes. GPC is widely distributed in human blood and saliva. L-α-glycerophosphoryl(choline-d9) (GPC-d9) is the deuterium-labeled form of GPC.
应用
GPC-d9 has been used as an internal standard in ultra-performance liquid chromatograph coupled to a SCIEX 4500QT mass spectrometer (UPLC-MS/MS) for the quantification of choline compounds from whole milk samples.
生化/生理作用
Glycerophosphocholine (GPC) protects mitochondrial respiratory complex I during oxidative stress associated with liver ischemia-reperfusion. GPC is an ergogenic supplement that improves muscle force production. The deuterium-labeled glycerophosphocholine is employed as an internal standard for human milk choline quantification using liquid chromatography-tandem mass spectrometry.
包装
5 mL Clear Glass Sealed Ampule (100403X-100ug)
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
美国出口管控1C298产品
Phosphatidylcholine biosynthesis in Mitis group streptococci via host metabolite scavenging
Journal of Bacteriology, 201(22), e00495-e00419 (2019)
Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine
Testing, 11(11) (2016)
Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance
Journal of the International Society of Sports Nutrition, 14(1), 39-39 (2017)
Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine
PLoS ONE, 11(11) (2016)
Variability of Water-Soluble Forms of Choline Concentrations in Human Milk during Storage, after Pasteurization, and among Women
Nutrients, 11(12), 3024-3024 (2019)
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