所有图片(1)
About This Item
线性分子式:
CH3(CH2)12COOCH(CH3)2
CAS号:
分子量:
270.45
FEMA编号:
3556
Beilstein:
1781127
EC 号:
欧洲委员会编号:
386
MDL编号:
UNSPSC代码:
12164502
PubChem化学物质编号:
Flavis编号:
9.105
NACRES:
NA.21
性状检查:
faint; fatty; oily
等级:
Fragrance grade
Halal
Kosher
Halal
Kosher
生物来源:
synthetic
Agency:
follows IFRA guidelines
食品过敏原:
no known allergens
推荐产品
生物来源
synthetic
质量水平
等级
Fragrance grade
Halal
Kosher
Agency
follows IFRA guidelines
管理合规性
EU Regulation 1223/2009
方案
≥98%
折射率
n20/D 1.434 (lit.)
沸点
193 °C/20 mmHg (lit.)
mp
~3 °C (lit.)
密度
0.85 g/mL at 25 °C (lit.)
应用
flavors and fragrances
文件
see Safety & Documentation for available documents
食品过敏原
no known allergens
致敏芳香化合物
no known allergens
性状检查
faint; fatty; oily
SMILES字符串
CCCCCCCCCCCCCC(=O)OC(C)C
InChI
1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI key
AXISYYRBXTVTFY-UHFFFAOYSA-N
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一般描述
肉豆蔻酸异丙酯主要用作化妆品和外用药物的增溶剂、乳化剂和润肤剂。它还被用作食品工业中的调味剂。
应用
- 负载富含黄酮类化合物的姜属植物纳米结构脂质载体的开发：本研究开发了用于从姜黄中提取的黄酮类化合物的纳米结构脂质载体，利用肉豆蔻酸异丙酯稳定这些载体并改善生物活性化合物的递送。（Shazwani SS 等人，2024 年）
- 利格列汀经皮递送物理和化学增强技术的比较评估：该研究比较了多种用于经皮药物递送的增强方法，包括使用异丙基肉豆蔻酸酯，突出了其在渗透增强技术中的有效性。（Karve T 等人，2024 年）
- 利用响应面法优化花椒酰胺脂质体条件及其在 Caco-2 细胞单层模型中的吸收特性：本研究优化了含有花椒酰胺的脂质体配方，其中肉豆蔻酸异丙酯在脂质体稳定性和吸收特性中至关重要。（Wang R 等人，2024 年）
生化/生理作用
1.0% 时的气味
10ppm 时的味道
免责声明
仅供R&D或非EU食品使用不用于零售。
储存分类代码
10 - Combustible liquids
WGK
awg
闪点(°F)
>302.0 °F
闪点(°C)
> 150 °C
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Handbook of Preservatives, 425-425 (2004)
T N Engelbrecht et al.
Skin pharmacology and physiology, 25(4), 200-207 (2012-05-23)
In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol, palmitic acid and cholesterol sulfate
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
Fan Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 158-163 (2012-06-21)
Transdermal delivery of methotrexate (MTX) was investigated by using the solid-in-oil (S/O) technique. Because MTX was coated with nonionic surfactant molecules, the resulting complex was easy to dissolve in various organic solvents and provided a transparent solution in isopropyl myristate
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
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