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Merck
CN

W297070

Sigma-Aldrich

丙酮酸

greener alternative

natural, ≥95%, FG

别名:

α-酮丙酸, 2-氧代戊二酸

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About This Item

线性分子式:
CH3COCOOH
CAS号:
分子量:
88.06
FEMA编号:
2970
Beilstein:
506211
EC 号:
欧洲委员会编号:
19c
MDL编号:
UNSPSC代码:
12164502
PubChem化学物质编号:
Flavis编号:
8.019
NACRES:
NA.21
性状检查:
caramel; acidic; sour
等级:
FG
Halal
Kosher
natural
食品过敏原:
no known allergens

等级

FG
Halal
Kosher
natural

质量水平

管理合规性

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 172.515

方案

≥95%

环保替代产品特性

Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

折射率

n20/D 1.428 (lit.)

沸点

165 °C (lit.)

mp

11-12 °C (lit.)

密度

1.267 g/mL at 25 °C (lit.)

应用

flavors and fragrances

文件

see Safety & Documentation for available documents

食品过敏原

no known allergens

环保替代产品分类

性状检查

caramel; acidic; sour

SMILES字符串

CC(=O)C(O)=O

InChI

1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)

InChI key

LCTONWCANYUPML-UHFFFAOYSA-N

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一般描述

天然存在: 芦笋、牛肉、清酒、弗吉尼亚烟草、小麦面包。

应用


  • 通过苹果酸酶生物催化和CO2固定高效合成L-苹果酸。:研究重点介绍了由丙酮酸生物催化合成L-苹果酸,展示了一种高效的CO2固定过程。该研究为使用丙酮酸作为前体的可持续化学生产开辟了新途径(Shi et al., 2024)。

  • H(2)S驱动的纳米马达通过诱导铁死亡和乳酸-丙酮酸轴紊乱来主动治疗肿瘤。:研究展示了使用硫化氢驱动的纳米马达进行肿瘤治疗,诱导铁死亡并破坏乳酸-丙酮酸代谢轴,展示了丙酮酸代谢在癌症治疗中的创新应用(Wang et al., 2024)。

生化/生理作用

5 ppm时具有味觉

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Corr. 1C

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 1

闪点(°F)

183.2 °F - closed cup

闪点(°C)

84 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Sarah C Atkinson et al.
Plant molecular biology, 81(4-5), 431-446 (2013-01-29)
Lysine is one of the most limiting amino acids in plants and its biosynthesis is carefully regulated through inhibition of the first committed step in the pathway catalyzed by dihydrodipicolinate synthase (DHDPS). This is mediated via a feedback mechanism involving
Emilie A Bard-Chapeau et al.
Nature genetics, 46(1), 24-32 (2013-12-10)
The most common risk factor for developing hepatocellular carcinoma (HCC) is chronic infection with hepatitis B virus (HBV). To better understand the evolutionary forces driving HCC, we performed a near-saturating transposon mutagenesis screen in a mouse HBV model of HCC.
Albert P Chen et al.
PloS one, 8(2), e56551-e56551 (2013-02-21)
Following radiation therapy (RT), tumor morphology may remain unchanged for days and sometimes weeks, rendering anatomical imaging methods inadequate for early detection of therapeutic response. Changes in the hyperpolarized [1-¹³C]lactate signals observed in vivo following injection of pre-polarized [1-¹³C]pyruvate has
Hannes Link et al.
Nature biotechnology, 31(4), 357-361 (2013-03-05)
Recent data suggest that the majority of proteins bind specific metabolites and that such interactions are relevant to metabolic and gene regulation. However, there are no methods to systematically identify functional allosteric protein-metabolite interactions. Here we present an experimental and
Robert A Jacobs et al.
American journal of physiology. Endocrinology and metabolism, 304(7), E686-E694 (2013-02-07)
Lactate is an important intermediate metabolite in human bioenergetics and is oxidized in many different tissues including the heart, brain, kidney, adipose tissue, liver, and skeletal muscle. The mechanism(s) explaining the metabolism of lactate in these tissues, however, remains unclear.

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