所有图片(1)
About This Item
线性分子式:
(CH3)2CHCO2H
CAS号:
分子量:
88.11
FEMA编号:
2222
Beilstein:
635770
EC 号:
欧洲委员会编号:
6
MDL编号:
UNSPSC代码:
12164502
PubChem化学物质编号:
Flavis编号:
8.006
NACRES:
NA.21
性状检查:
butter; acidic; rancid
等级:
FG
Kosher
Kosher
生物来源:
synthetic
Agency:
meets purity specifications of JECFA
食品过敏原:
no known allergens
推荐产品
生物来源
synthetic
质量水平
等级
FG
Kosher
Agency
meets purity specifications of JECFA
管理合规性
EU Regulation 1334/2008 & 872/2012
FCC
FDA 21 CFR 172.515
蒸汽密度
3.04 (vs air)
蒸汽压
1.5 mmHg ( 20 °C)
方案
≥99%
自燃温度
824 °F
expl. lim.
10 %
折射率
n20/D 1.393 (lit.)
沸点
153-154 °C (lit.)
mp
−47 °C (lit.)
密度
0.95 g/mL at 25 °C (lit.)
应用
flavors and fragrances
文件
see Safety & Documentation for available documents
食品过敏原
no known allergens
性状检查
butter; acidic; rancid
SMILES字符串
CC(C)C(O)=O
InChI
1S/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6)
InChI key
KQNPFQTWMSNSAP-UHFFFAOYSA-N
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一般描述
Isobutyric acid is a volatile fatty acid that can be used as a flavoring agent. It occurs naturally in Ceratonia siliqua L. The gum obtained from the kernels of this species is used as a thickener in the food industry.
应用
- Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody.: This study presents groundbreaking research on how isobutyric acid can enhance the efficacy of anti-PD-1 antibodies, offering significant implications for improving cancer immunotherapy treatments (Murayama et al., 2024).
生化/生理作用
10ppm 时的气味
15ppm 时的味道
其他说明
天然存在：罗马洋甘菊、草莓、乳制品。
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
131.0 °F - closed cup
闪点(°C)
55 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Effect of temperature on isobutyric acid loss during roasting of carob kibble
Berna A, et al
Journal of Agricultural and Food Chemistry, 45(10), 4084-4087 (1997)
Manipulation of colonic bacteria and volatile fatty acid production by dietary high amylose maize (amylomaize) starch granules
Wang X, et al
Journal of Applied Microbiology, 93(3), 390-397 (2002)
Burdock GA
Encyclopedia of Food and Color Additives, 1, 1463-1464 (1997)
Julia Biermann et al.
Molecular vision, 17, 395-403 (2011-02-12)
Histone deacetylase inhibitors (HDACi) have neuroprotective effects under various neurodegenerative conditions, e.g., after optic nerve crush (ONC). HDACi-mediated protection of central neurons by increased histone acetylation has not previously been demonstrated in rat retinal ganglion cells (RGCs), although epigenetic changes
Kimberlee S Mix et al.
Molecular pharmacology, 65(2), 309-318 (2004-01-27)
Matrix metalloproteinases (MMPs) degrade extracellular matrix components, and overexpression of these enzymes contributes to tissue destruction in arthritis. Of particular importance are the collagenases, MMP-1 and MMP-13, which have high activity against the interstitial collagens in cartilage. In this study
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