T90301
3-(2-羟乙基)吲哚
97%
别名:
2-（3-吲哚基）乙醇, 3-吲哚乙醇, IEA, NSC 3884, 色醇
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关于此项目
经验公式（希尔记法）:
C10H11NO
化学文摘社编号:
分子量:
161.20
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-393-2
Beilstein/REAXYS Number:
125553
MDL number:
Assay:
97%
InChI
1S/C10H11NO/c12-6-5-8-7-11-10-4-2-1-3-9(8)10/h1-4,7,11-12H,5-6H2
InChI key
MBBOMCVGYCRMEA-UHFFFAOYSA-N
SMILES string
OCCc1c[nH]c2ccccc12
assay
97%
Quality Level
mp
56-59 °C (lit.)
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Application
作为反应物用于制备：
- RNA聚合酶ⅡC末端结构域抑制剂及其抗肿瘤活性
- 抗-HIV-1试剂
- 蛋白质与蛋白质的相互作用的抑制剂
- 羟色胺5-HT1A受体的部分激动剂
- 生长激素促分泌剂
- 血管内皮生长因子（VEGF）抑制剂
- A2B腺苷受体配体
- 十字花科植物抗毒素黄铜素的潜在解毒抑制剂
- 白细胞介素6抑制剂
- 双重结合位点乙酰胆碱酯酶抑制剂
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Hao Chen et al.
Genes & development, 20(9), 1150-1161 (2006-04-19)
Many fungi undergo a developmental transition from a unicellular yeast form to an invasive filamentous form in response to environmental cues. Here we describe a quorum signaling pathway that links environmental sensing to morphogenesis in Saccharomyces cerevisiae. Saccharomyces cells secrete
Richard Pozdrik et al.
Journal of agricultural and food chemistry, 54(17), 6123-6129 (2006-08-17)
The disappearance of riboflavin absorbance at 445 nm from beers or model beers on light exposure is directly linked to light-struck character formation. The addition of (+)-catechin, (-)-epicatechin, tryptophol, or ascorbic acid was able to reduce, but not stop, absorbance
Xuqing Zhang et al.
Organic letters, 7(10), 2043-2046 (2005-05-07)
The tetrahydro-pyrano[3,4-b]indoles 6 were synthesized from 2-(2-trimethylsilanyl-1H-indol-3-yl)-ethanols 5 and various ketones or aldehydes through silicon-directed oxa-Pictet-Spengler cyclizations. An unusual reaction led to the dimeric products 7 when some of 5 was treated with acetone using BF(3) as the catalyst.
Dina Morshedi et al.
The FEBS journal, 274(24), 6415-6425 (2007-11-22)
Amyloid aggregation of polypeptides is related to a growing number of pathologic states known as amyloid disorders. There is a great deal of interest in developing small molecule inhibitors of the amyloidogenic processes. In the present article, the inhibitory effects
Ivan Kosalec et al.
Arhiv za higijenu rada i toksikologiju, 62(1), 41-49 (2011-03-23)
Tryptophol is an aromatic alcohol and secondary metabolite of the opportunistic fungus Candida albicans. Although its toxicity profile at cell level has been poorly investigated, recent data point to cytotoxic, cytostatic, and genotoxic effects in lymphocytes and the induction of
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