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Merck
CN
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文件

安全信息

T85308

Sigma-Aldrich

三(2-氯乙基)胺 盐酸盐

98%

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线性分子式:
(ClCH2CH2)3N·HCl
CAS号:
817-09-4
分子量:
240.99
EC 号:
212-442-3
MDL编号:
MFCD00012520
UNSPSC代码:
12352100
PubChem化学物质编号:
24900538

质量水平

100

检测方案

98%

mp

127-130 °C (lit.)

SMILES字符串

Cl.ClCCN(CCCl)CCCl

InChI

1S/C6H12Cl3N.ClH/c7-1-4-10(5-2-8)6-3-9;/h1-6H2;1H

InChI key

VEAUDLLZYJVHRI-UHFFFAOYSA-N

警示用语：

Danger

危险声明

H300,H314,H351

危险分类

Acute Tox. 2 Oral - Carc. 2 - Skin Corr. 1B

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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L Szinicz et al.
Arzneimittel-Forschung, 31(10), 1713-1717 (1981-01-01)
The effect of tris-(2-chloroethyl)-amine (HN-3) on RNA and DNA was investigated spectrophotometrically. The shift in the absorbance spectrum caused by the addition of HN-3 was used to test a variety of compounds for their ability to inhibit RNA alkylation. The
N I Riabchenko et al.
Radiobiologiia, 31(1), 22-26 (1991-01-01)
Regularities of chromatin degradation in thymocytes and LS/BL tumor cells have been investigated. It has been shown that the rate of DNA degradation by Ca/Mg-dependent endonuclease in LS/BL tumor cells is 25 times lower than that in thymocytes, and radiation
Trichloromethyl ketones as synthetically versatile donors: application in direct catalytic mannich-type reactions and the stereoselective synthesis of azetidines.
Hiroyuki Morimoto et al.
Angewandte Chemie (International ed. in English), 45(19), 3146-3150 (2006-04-06)
D B Wildenauer et al.
Biochimica et biophysica acta, 603(1), 101-116 (1980-12-02)
The influence of tris(2-chloroethyl)amine on shape changes of human erythrocytes and ghosts was studied in vitro and correlated with alterations in the molecular structure of the membrane. (1) Reaction with 1--2 mM tris(2-chloroethyl)amine, a concentration which caused polymerisation of spectrin
T Hiratsuka
Biochemistry, 27(11), 4110-4114 (1988-05-31)
The chemotherapeutic alkylating reagent tris(2-chloroethyl)amine (TCEA) was used as a trifunctional cross-linking reagent with a cross-linking span of 5 A for myosin subfragment 1 (S-1). When S-1 was incubated with TCEA, all three domains of 20, 26, and 50 kDa
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