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Merck
CN

T62804

Sigma-Aldrich

1,1,1-三氟丙酮

97%

别名:

α,α,α-三氟丙酮, 1,1,1-三氟-2-丙酮, 3,3,3-三氟丙酮, 三氟甲基甲酮, 甲基三氟甲基酮

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About This Item

线性分子式:
CH3COCF3
CAS号:
分子量:
112.05
Beilstein:
1748614
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽压

13.62 psi ( 20 °C)

质量水平

方案

97%

折射率

n20/D 1.3 (lit.)

沸点

22 °C (lit.)

密度

1.252 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

CC(=O)C(F)(F)F

InChI

1S/C3H3F3O/c1-2(7)3(4,5)6/h1H3

InChI key

FHUDAMLDXFJHJE-UHFFFAOYSA-N

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应用

用于以 2,6-二卤吡啶为原料合成 2-三氟甲基-7-氮杂吲哚。该手性亚胺衍生物用于通过 Strecker 反应和随后的腈水解或还原反应,制备对映纯 α-三氟甲基丙氨酸和二胺。

象形图

FlameCorrosion

警示用语:

Danger

危险声明

危险分类

Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 1 - Skin Corr. 1B

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

-22.0 °F - closed cup

闪点(°C)

-30 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Florent Huguenot et al.
The Journal of organic chemistry, 71(18), 7075-7078 (2006-08-26)
Diastereomerically pure alpha-trifluoromethyl alpha-amino nitriles obtained by Strecker-type reactions from chiral CF3 imines and iminium proved to be very attractive versatile intermediates for the synthesis of various alpha-trifluoromethyl amino compounds. From these synthons, both enantiomers of alpha-trifluoromethyl alanine, trifluoromethyl 1,2-diamines
Synthesis, 251-251 (2007)
Sheida Esmaielzadeh et al.
Acta chimica Slovenica, 63(2), 351-362 (2016-06-23)
Some cobalt(III) complexes with a potentially tetradentate unsymmetrical NNOS Schiff base ligand have been synthesized and characterized using IR, 1HNMR, UV-Vis spectroscopy and elemental analysis. The equilibrium constants were measured spectrophotometrically for 1:1 adduct formation of the cobalt(III) complexes with
Emre Kinaci et al.
Polymers, 12(9) (2020-09-20)
In this investigation, the terminal double bonds of the side chain epoxidized cardanol glycidyl ether (SCECGE) molecule were further epoxidized in the presence of Oxone® (potassium peroxomonosulfate) and fluorinated acetone. Regular methods for the double bond epoxidation are not effective
Jobst Liebau et al.
The Journal of biological chemistry, 295(29), 9868-9878 (2020-05-22)
Fold-switch pathways remodel the secondary structure topology of proteins in response to the cellular environment. It is a major challenge to understand the dynamics of these folding processes. Here, we conducted an in-depth analysis of the α-helix-to-β-strand and β-strand-to-α-helix transitions

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