检测方案
99%
bp
258-259 °C (lit.)
mp
102-104 °C (lit.)
密度
1.062 g/mL at 25 °C (lit.)
SMILES字符串
Cc1ccccc1C(O)=O
InChI
1S/C8H8O2/c1-6-4-2-3-5-7(6)8(9)10/h2-5H,1H3,(H,9,10)
InChI key
ZWLPBLYKEWSWPD-UHFFFAOYSA-N
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一般描述
邻苯甲酸是一种芳香羧酸，是一种用于农药和医药的有机中间体。
WGK
WGK 3
闪点(°F)
298.4 °F
闪点(°C)
148 °C
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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The iron(II)- and 2-oxoglutarate (2OG)-dependent dioxygenase AlkB from Escherichia coli (EcAlkB) repairs alkylation damage in DNA by direct reversal. EcAlkB substrates include methylated bases, such as 1-methyladenine (m(1)A) and 3-methylcytosine (m(3)C), as well as certain bulkier lesions, for example the
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The Escherichia coli AlkB protein (EcAlkB) is a DNA repair enzyme which reverses methylation damage such as 1-methyladenine (1-meA) and 3-methylcytosine (3-meC). The mammalian AlkB homologues ALKBH2 and ALKBH3 display EcAlkB-like repair activity in vitro, but their substrate specificities are
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Journal of Liquid Chromatography and Related Technologies, 25, 2709-2715 (2002)
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ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly contributing to tumor formation and used in cancer therapy.
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