推荐产品
方案
>90% (HPLC)
表单
solid or viscous liquid
反应适用性
reaction type: Pegylations
聚合物结构设计
functionality: monofunctional
运输
ambient
储存温度
−20°C
SMILES字符串
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)NC(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)COCC
特点和优势
MAL-dPEG12-Tris(-dPEG24-acid)3 is a thiol- and amine-reactive, four-arm, monodispersed PEG with one arm shorter than the other three. This product is useful for charge modulation and elimination of renal clearance in drug delivery and imaging applications, among others. The dPEG spacer length from the maleimide olefin to the carbonyl carbon on each of the three long arms is 129 atoms. The average distance from maleimide to carbonyl carbon is 80.4 Å.
法律信息
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Haiming Ding et al.
Bioconjugate chemistry, 24(11), 1945-1954 (2013-11-02)
The tumor-associated glycoprotein-72 (TAG-72) antigen is highly overexpressed in various human adenocarcinomas and anti-TAG-72 monoclonal antibodies, and fragments are therefore useful as pharmaceutical targeting vectors. In this study, we investigated the effects of site-specific PEGylation with MW 2-4 kDa discrete
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