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Merck
CN

QBD10866

Sigma-Aldrich

SPDP-dPEG®36-acid

>95% (HPLC)

别名:

OPSS-PEG1500-acid, OPSS-PEG36-acid, SPDP-PEG-acid, SPDP-PEG36-COOH, SPDP-PEG36-acid

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About This Item

经验公式(希尔记法):
C83H158N2O39S2
分子量:
1872.26
MDL编号:
UNSPSC代码:
12352106
NACRES:
NA.22

方案

>95% (HPLC)

表单

solid or viscous liquid

反应适用性

reaction type: Pegylations

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES字符串

S(Sc1ncccc1)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

InChI

1S/C83H158N2O39S2/c86-81(5-80-125-126-82-3-1-2-6-85-82)84-7-9-90-11-13-92-15-17-94-19-21-96-23-25-98-27-29-100-31-33-102-35-37-104-39-41-106-43-45-108-47-49-110-51-53-112-55-57-114-59-61-116-63-65-118-67-69-120-71-73-122-75-77-124-79-78-123-76-74-121-72-7

InChI key

YETQZNCXLDFCHR-UHFFFAOYSA-N

特点和优势

SPDP-dPEG36-acid is a crosslinking reagent designed to conjugate free amines and sulfhydryls. The single molecular weight (i.e., monodispersed) PEG crossbridge between the two functional groups is 115 atoms (137.8 Å) long. Using a suitable carbodiimide, such as EDC, the propionic acid group reacts with free primary amines to form amide bonds. The pyridyl disulfide (SPDP, also known as OPSS) functional group reacts with free thiols to form disulfide bonds. This product is useful for crosslinking peptides, proteins, and small molecules, and modifying surfaces with suitable reactive sites. SPDP-dPEG36-acid is a monodisperse equivalent of the polymeric PEG1500.

法律信息

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

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