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Merck
CN

QBD10593

Sigma-Aldrich

DBCO-dPEG ®12-MAL

别名:

Polyethylene glycol

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About This Item

经验公式(希尔记法):
C52H74N4O17
分子量:
1027.16
UNSPSC代码:
51171641
NACRES:
NA.22

检测方案

>90%

形式

solid or viscous liquid

反应适用性

reagent type: cross-linking reagent
reaction type: click chemistry

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES字符串

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)NCCC(N2C3=C(C#CC4=C(C2)C=CC=C4)C=CC=C3)=O

一般描述

DBCO-dPEG®12-MAL is a versatile heterobifunctional cross-linking reagent used in strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. This approach is also known as copper-free click chemistry. The presence of maleimidopropyl (MAL) functional group in the reagent forms a thiol-ether linkage with sulfhydryl groups.

特点和优势

DBCO-dPEG ®₁₂-MAL can be used to conjugate two different proteins or an antibody with a payload by using copper-free "click" chemistry with the DBCO and reaction of the maleimide with a free thiol.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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