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Merck
CN

QBD10512

Sigma-Aldrich

Azido-dPEG®8-acid

别名:

Polyethylene glycol

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About This Item

经验公式(希尔记法):
C19H37N3O10
分子量:
467.51
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22

方案

>90%

表单

solid or viscous liquid

反应适用性

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

官能团

azide
carboxylic acid

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES字符串

OC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

InChI

1S/C19H37N3O10/c20-22-21-2-4-26-6-8-28-10-12-30-14-16-32-18-17-31-15-13-29-11-9-27-7-5-25-3-1-19(23)24/h1-18H2,(H,23,24)

InChI key

URUGOEBULOZLBF-UHFFFAOYSA-N

特点和优势

The azido-dPEG®8 contains an azide function on one end of a single molecular weight dPEG® spacer (32.2Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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