QBD10502
Azido-dPEG®4-acid
别名:
15-Azido-4,7,10,13-tetraoxapentadecanoic acid, 3-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid, Polyethylene glycol
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关于此项目
经验公式（希尔记法）:
C11H21N3O6
化学文摘社编号:
分子量:
291.30
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
InChI
1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16)
SMILES string
OC(CCOCCOCCOCCOCCN=[N+]=[N-])=O
InChI key
BODPHGOBXPGJKO-UHFFFAOYSA-N
assay
>90%
form
solid or viscous liquid
reaction suitability
reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry
functional group
azide
carboxylic acid
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
The azido-dPEG®4 contains an azide function on one end of a single molecular weight dPEG® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The acid function may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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