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Merck
CN

QBD10502

Sigma-Aldrich

Azido-dPEG®4-acid

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别名:
15-Azido-4,7,10,13-tetraoxapentadecanoic acid, 3-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid, Polyethylene glycol
经验公式(希尔记法):
C11H21N3O6
分子量:
291.30
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22

检测方案

>90%

形式

solid or viscous liquid

反应适用性

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

官能团

azide
carboxylic acid

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES字符串

OC(CCOCCOCCOCCOCCN=[N+]=[N-])=O

InChI

1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16)

InChI key

BODPHGOBXPGJKO-UHFFFAOYSA-N

特点和优势

The azido-dPEG®4 contains an azide function on one end of a single molecular weight dPEG® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The acid function may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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