QBD10501
Azido-dPEG®4-NHS ester
别名:
3-(Azidotetra(ethyleneoxy))propionic acid succinimidyl ester, NHS-Peg4-Azide, Polyethylene glycol
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关于此项目
经验公式（希尔记法）:
C15H24N4O8
化学文摘社编号:
分子量:
388.37
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
shipped in
ambient
storage temp.
−20°C
InChI
1S/C15H24N4O8/c16-18-17-4-6-24-8-10-26-12-11-25-9-7-23-5-3-15(22)27-19-13(20)1-2-14(19)21/h1-12H2
SMILES string
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCN=[N+]=[N-]
InChI key
OIGKWPIMJCPGGD-UHFFFAOYSA-N
assay
>90%
form
solid or viscous liquid
reaction suitability
reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry
functional group
NHS ester
azide
polymer architecture
shape: linear
functionality: heterobifunctional
Features and Benefits
The azido-dPEG®4-NHS ester contains an azide function on one end of a single molecular weight dPEG® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. NHS ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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