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方案
>90%
表单
solid or viscous liquid
反应适用性
reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry
官能团
NHS ester
azide
聚合物结构设计
shape: linear
functionality: heterobifunctional
运输
ambient
储存温度
−20°C
SMILES字符串
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCN=[N+]=[N-]
InChI
1S/C15H24N4O8/c16-18-17-4-6-24-8-10-26-12-11-25-9-7-23-5-3-15(22)27-19-13(20)1-2-14(19)21/h1-12H2
InChI key
OIGKWPIMJCPGGD-UHFFFAOYSA-N
特点和优势
The azido-dPEG®4-NHS ester contains an azide function on one end of a single molecular weight dPEG® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. NHS ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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