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Merck
CN

QBD10319

Sigma-Aldrich

m-dPEG®24-MAL

别名:

Polyethylene glycol

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About This Item

经验公式(希尔记法):
C56H106N2O27
分子量:
1239.44
MDL编号:
UNSPSC代码:
51171641
PubChem化学物质编号:
NACRES:
NA.22

方案

>90%

表单

solid or viscous liquid

反应适用性

reactivity: thiol reactive
reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: sulfhydryl reactive

聚合物结构设计

shape: linear
functionality: monofunctional

运输

ambient

储存温度

−20°C

SMILES字符串

O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)CCN1C(C=CC1=O)=O

InChI

1S/C56H106N2O27/c1-62-8-9-64-12-13-66-16-17-68-20-21-70-24-25-72-28-29-74-32-33-76-36-37-78-40-41-80-44-45-82-48-49-84-52-53-85-51-50-83-47-46-81-43-42-79-39-38-77-35-34-75-31-30-73-27-26-71-23-22-69-19-18-67-15-14-65-11-10-63-7-5-57-54(59)4-6-58-55(60)2-

InChI key

IRQWFNZIEAPTBJ-UHFFFAOYSA-N

特点和优势

The m-dPEG®24-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®24-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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