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Merck
CN

QBD10211

Sigma-Aldrich

m-dPEG®4-NHS ester

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别名:
2,5-Dioxo-1-pyrrolidinyl 4,7,10,13-tetraoxatetradecanoate, Polyethylene glycol, Triethylene glycol methyl ether 2-(succinimidyloxycarbonyl)ethyl ether
经验公式(希尔记法):
C14H23NO8
分子量:
333.33
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.22

检测方案

>90%

形式

solid or viscous liquid

反应适用性

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: amine reactive

聚合物结构设计

shape: linear
functionality: monofunctional

运输

ambient

储存温度

−20°C

SMILES字符串

O=C1CCC(N1OC(CCOCCOCCOCCOC)=O)=O

InChI

1S/C14H23NO8/c1-19-6-7-21-10-11-22-9-8-20-5-4-14(18)23-15-12(16)2-3-13(15)17/h2-11H2,1H3

InChI key

MAYFFZZPEREGBQ-UHFFFAOYSA-N

特点和优势

The m-dPEG®4-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®4-NHS (N-hydroxysuccinimide) ester reacts with amines.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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