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Merck
CN

QBD10203

Sigma-Aldrich

TFP-dPEG®4-biotinidase resistant biotin

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About This Item

经验公式(希尔记法):
C31H44F4N4O9S
分子量:
724.76
UNSPSC代码:
51171641
PubChem化学物质编号:
NACRES:
NA.22

方案

>90%

表单

solid or viscous liquid

反应适用性

reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: amine reactive

reagent type: linker

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES字符串

O=C1NC(C2N1)CSC2CCCCC(NC(C(NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O)=O)CC)=O

InChI

1S/C31H44F4N4O9S/c1-2-21(37-24(40)6-4-3-5-23-28-22(18-49-23)38-31(43)39-28)30(42)36-8-10-45-12-14-47-16-15-46-13-11-44-9-7-25(41)48-29-26(34)19(32)17-20(33)27(29)35/h17,21-23,28H,2-16,18H2,1H3,(H,36,42)(H,37,40)(H2,38,39,43)

InChI key

IOOKENPHEAMTTM-UHFFFAOYSA-N

特点和优势

TFP-dPEG®4-biotinidase resistant biotin contains an amine reactive TFP ester and chemically modified biotin that is stable in the presence of biotinidase. Resistance to biotinidase cleavage of biotin is necessary in some biotechnology applications. The chemical modification to biotin imparts resistance to biotinidase cleavage without reducing the strength of biotin-avidin binding. The single molecular weight dPEG® spacer imparts water solubility, prevents aggregation and precipitation of labeled peptides and proteins, and reduces non-specific binding. Two different single molecular weight dPEG® spacers are available for precise spatial control between the modified biotin and the surface of the molecule to which it is conjugated.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

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