QBD10194
NHS-S-S-dPEG®4-biotin (cleavable)
别名:
2,5-Dioxo-1-pyrrolidinyl 29-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-9,25-dioxo-12,15,18,21-tetraoxa-4,5-dithia-8,24-diazanonacosanoate, Polyethylene glycol
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About This Item
经验公式（希尔记法）:
C30H49N5O11S3
CAS号:
分子量:
751.93
UNSPSC代码:
51171641
PubChem化学物质编号:
NACRES:
NA.22
检测方案
>90%
形式
solid or viscous liquid
反应适用性
reaction type: Biotinylations
reagent type: cross-linking reagent
官能团
disulfide
聚合物结构设计
shape: linear
functionality: monofunctional
运输
ambient
储存温度
−20°C
SMILES字符串
O=C(NCCSSCCC(ON1C(CCC1=O)=O)=O)CCOCCOCCOCCOCCNC(CCCCC2C3NC(NC3CS2)=O)=O
特点和优势
NHS-S-S-dPEG®4-biotin is used extensively to label molecules that contain a free amine with biotin. This dPEG® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin. NHS-S-S-dPEG®4-biotin contains a disulfide group in the linear chain, allowing the biotin to be cleaved reductively from the labeled molecule.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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