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Merck
CN

QBD10119

Sigma-Aldrich

Acid-dPEG®9-NHS ester

别名:

Polyethylene glycol

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About This Item

经验公式(希尔记法):
C26H45NO15
分子量:
611.63
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22

方案

>90%

表单

solid or viscous liquid

反应适用性

reagent type: cross-linking reagent
reactivity: amine reactive

官能团

NHS ester
carboxylic acid

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES字符串

OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O

InChI

1S/C26H45NO15/c28-23-1-2-24(29)27(23)42-26(32)4-6-34-8-10-36-12-14-38-16-18-40-20-22-41-21-19-39-17-15-37-13-11-35-9-7-33-5-3-25(30)31/h1-22H2,(H,30,31)

InChI key

BJOKQEMLFQBOQZ-UHFFFAOYSA-N

特点和优势

Acid-dPEG®9-NHS ester is a unique heterobifunctional dPEG® crosslinking product which allows conjugation to two different moieties, each containing free amines. Because the single molecular weight dPEG® spacers contain an N-hydroxysuccinimide ester only on one end of the spacer, greater control of the conjugation reaction can be maintained. The free acid end of the spacer can be left unreacted to modify the surface properties of the molecule to which it is conjugated, or the free acid end can be activated and conjugated to a different group at a later time. The dPEG® spacers provide precise spacing/distance control, and the dPEG® itself provides the well-known benefits of increased water solubility; decreased immunogenicity; protection from proteolysis; increased hydrodynamic volume; and increased serum half-life.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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