检测方案
>90%
形式
solid or viscous liquid
反应适用性
reaction type: Biotinylations
reaction type: Biotinylations
reactivity: amine reactive
reagent type: cross-linking reagent
聚合物结构设计
shape: linear
functionality: monofunctional
运输
ambient
储存温度
−20°C
SMILES字符串
O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O
应用
Biotin-dPEG®4-TFP ester is an amphiphilic and hydrolytically stable compound used as a cross-linking reagent in biotinylations reactions.
特点和优势
Biotin-dPEG®4-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety which hydrolyzes more slowly than NHS ester in aqueous media and are more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®4-TFP ester has a long spacer of precise length (19.2 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. The PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Bioconjugate techniques
Bioconjugate Techniques (2013)
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