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方案
>90%
表单
solid or viscous liquid
反应适用性
reaction type: Biotinylations
reaction type: Biotinylations
reactivity: amine reactive
reagent type: cross-linking reagent
聚合物结构设计
shape: linear
functionality: monofunctional
运输
ambient
储存温度
−20°C
SMILES字符串
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)OC3=C(C(F)=CC(F)=C3F)F
InChI
1S/C43H69F4N3O16S/c44-33-31-34(45)40(47)42(39(33)46)66-38(52)5-7-54-9-11-56-13-15-58-17-19-60-21-23-62-25-27-64-29-30-65-28-26-63-24-22-61-20-18-59-16-14-57-12-10-55-8-6-48-37(51)4-2-1-3-36-41-35(32-67-36)49-43(53)50-41/h31,35-36,41H,1-30,32H2,(H,48,51)(H
InChI key
YQTIPJSYUMZZNU-UHFFFAOYSA-N
特点和优势
Biotin-dPEG®12-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety whcih hydrolyze more slowly than NHS esters in aqueous media and is more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®12-TFP ester has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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