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Merck
CN

QBD10007

Sigma-Aldrich

Biotin-dPEG®24-TFP ester

别名:

Polyethylene glycol

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About This Item

经验公式(希尔记法):
C67H117F4N3O28S
分子量:
1520.71
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.22

方案

>90%

表单

solid or viscous liquid

反应适用性

reaction type: Biotinylations
reaction type: Biotinylations
reactivity: amine reactive

reagent type: cross-linking reagent

聚合物结构设计

shape: linear
functionality: monofunctional

运输

ambient

储存温度

−20°C

SMILES字符串

O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O

InChI key

DZXHDWHQLGLRLF-UHFFFAOYSA-N

特点和优势

The Biotin-dPEG®24-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety which hydrolyze more slowly than NHS esters in aqueous media and are more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®24-TFP ester has a long spacer of precise length (99.3 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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