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Merck
CN

P51559

Sigma-Aldrich

丙酰氯

98%

别名:

丙酰氯, 乙基氯仿, 普罗里酰氯, 氯乙酮

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About This Item

线性分子式:
CH3CH2COCl
CAS号:
分子量:
92.52
Beilstein:
385632
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

蒸汽密度

3.2 (vs air)

质量水平

方案

98%

折射率

n20/D 1.404 (lit.)

沸点

77-79 °C (lit.)

mp

−94 °C

密度

1.059 g/mL at 25 °C (lit.)

SMILES字符串

CCC(Cl)=O

InChI

1S/C3H5ClO/c1-2-3(4)5/h2H2,1H3

InChI key

RZWZRACFZGVKFM-UHFFFAOYSA-N

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一般描述

丙酰氯是一种重要化学中间体,用于合成各种丙酸衍生物。。

应用

丙酰氯可用作以下反应的酰化剂:
  • 在氯化铟(InCl3)浸染的介孔Si-MCM-41催化剂作用下,将苯甲醚转化为4-间甲氧基苯丙酮以及2-甲氧基萘转化为1-丙氧基-2-甲氧基萘。

此外,还可用于:
  • 在存在硫酰氯和过氧化物的条件下氯化,形成α-氯丙酰氯和β-氯丙酰氯。
  • 与(羟丙基)纤维素反应生成丙酸酯、[(丙酰氧基)丙基]纤维素。

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

补充剂危害

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

42.8 °F - closed cup

闪点(°C)

6 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Douglas T Durig et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 60(7), 1481-1504 (2004-05-19)
Variable temperature (-60 to -100 degrees C) studies of the infrared spectra (3500-400 cm(-1)) of propionyl fluoride (CH3CH2CFO) and 2-methylpropionyl fluoride ((CH3)2CHCFO), dissolved in liquid xenon have been recorded. From these data, the enthalpy difference has been determined to be
Chlorinations with Sulfuryl Chloride. III.(a) The Peroxide-Catalyzed Chlorination of Aliphatic Acids and Acid Chlorides.(b) The Photochemical Sulfonation of Aliphatic Acids
Kharasch MS and Brown HC
Journal of the American Chemical Society, 62(4), 925-929 (1940)
The propanoate ester of (2-hydroxypropyl) cellulose: a thermotropic cholesteric polymer that reflects visible light at ambient temperatures
Tseng SL, et L.
Macromolecules, 15(5), 1262-1264 (1982)
Joanna Kurczewska et al.
International journal of pharmaceutics, 486(1-2), 226-231 (2015-04-07)
Vancomycin was immobilized on three different organically functionalized silicas. The materials obtained were used for a controlled release of the antibiotic. The influence of the type of chemical bond on the in vitro drug release was investigated. A weak ionic
Acylation of aromatic compounds using moisture insensitive InCl3 impregnated mesoporous Si-MCM-41 catalyst
Choudhary VR, et al.
Tetrahedron Letters, 43(6), 1105-1107 (2002)

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