推荐产品
质量水平
检测方案
98%
包含
≤2.5% water
折射率
n20/D 1.449 (lit.)
bp
83 °C (lit.)
密度
0.86 g/mL at 25 °C (lit.)
储存温度
2-8°C
SMILES字符串
NCC#C
InChI
1S/C3H5N/c1-2-3-4/h1H,3-4H2
InChI key
JKANAVGODYYCQF-UHFFFAOYSA-N
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应用
通过碳水化合物连接型氨基酸的炔丙基酰胺与 9,10-双(叠氮甲基)蒽进行 1,3-偶极环加成反应,合成手性、荧光大环类化合物。
警示用语:
Danger
危险分类
Acute Tox. 2 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Journal of neural transmission (Vienna, Austria : 1996), 120(6), 893-902 (2012-12-15)
Alzheimer's disease (AD) is a complex neurodegenerative disorder with a multifaceted pathogenesis. There are at present three Food and Drug Administration-approved drugs based on the "one drug, one target" paradigm (donepezil, galantamine and rivastigmine) that improve symptoms by inhibiting acetylcholinesterase.
Proceedings of the National Academy of Sciences of the United States of America, 112(9), 2752-2757 (2015-03-03)
With its noncatalytic domains, DNA-binding regions, and a catalytic core targeting the histone tails, LSD1-CoREST (lysine-specific demethylase 1; REST corepressor) is an ideal model system to study the interplay between DNA binding and histone modification in nucleosome recognition. To this
Chemical communications (Cambridge, England), 48(12), 1811-1813 (2012-01-06)
Promoted by diethyl azodicarboxylate, a novel and highly stereoselective synthesis of cis-β-enaminones via oxidative dehydrogenation and hydration of the substituted propargylamines was realized. The possible mechanism was also proposed.
Chemistry (Weinheim an der Bergstrasse, Germany), 16(37), 11443-11454 (2010-08-21)
The first highly efficient and stereoselective difluoromethylation of structurally diverse N-tert-butylsulfinyl ketimines has been achieved with an in situ generated PhSO(2)CF(2)(-) anion, which provides a powerful synthetic method for the preparation of a variety of structurally diverse homochiral α-difluoromethyl tertiary
Organic & biomolecular chemistry, 8(20), 4575-4581 (2010-08-27)
A new, heterogeneous, 4 A molecular sieve-supported copper(ii) catalyst was developed and was used successfully in the A(3) coupling of alkynes, aldehydes and amines under simple reaction conditions.
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