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兴奋性神经毒素，证明可引起类似于 Huntington 疾病的脑损伤。
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Danger
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危险分类
Acute Tox. 3 Oral
WGK
WGK 3
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Not applicable
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Not applicable
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Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Emmanuel Brouillet et al.
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Huntington's disease (HD) is a neurodegenerative disorder caused by a mutation in the gene encoding Huntingtin. The mechanisms underlying the preferential degeneration of the striatum, the most striking neuropathological change in HD, are unknown. Of those probably involved, mitochondrial defects
C V Borlongan et al.
Neuroscience and biobehavioral reviews, 21(3), 289-293 (1997-05-01)
Huntington's disease (HD) is a progressive neurodegenerative disorder associated with severe degeneration of basal ganglia neurons, especially the intrinsic neurons of the striatum, and characterized by progressive dementia and involuntary abnormal choreiform movements. Despite our increasing knowledge of the pathophysiology
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The study was designed to investigate the beneficial effect of quercetin supplementation in 3-nitropropionic acid (3-NP) induced model of Huntington's disease (HD). HD was induced in rats by administering sub-chronic dose of 3-NP, intraperitoneally, twice daily for 17days. Quercetin was
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